Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.46 |
| ▸ | YAP1 | P46937 | 1/20 | 0.46 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.46 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808054 | 0.92 | HTT (0.49) | ALDH1A1HTTLMNAMAPTPOLB | |
| SCHEMBL9808064 | 0.89 | HPGD (0.53) | ALDH1A1LMNAMAPTGAAKDM4E | |
| SCHEMBL9808177 | 0.87 | HTT (0.59) | ALDH1A1HTTLMNAMAPTPOLB | |
| SCHEMBL9808092 | 0.87 | HPGD (0.46) | ALDH1A1HTTLMNAMAPTGAA | |
| SCHEMBL9808307 | 0.83 | HTT (0.53) | ALDH1A1HTTLMNAMAPTPOLB | |
| SCHEMBL9808182 | 0.82 | MAPT (0.53) | ALDH1A1HTTLMNAMAPTPOLB | |
| SCHEMBL9808246 | 0.79 | ALDH1A1 (0.66) | ALDH1A1HTTLMNAPOLBPKM | |
| SCHEMBL9808286 | 0.78 | HTT (0.56) | ALDH1A1HTTLMNAMAPTPOLB | |
| SCHEMBL9808172 | 0.78 | TDP1 (0.45) | ALDH1A1MAPTPOLBKDM4EHPGD | |
| SCHEMBL9808214 | 0.78 | HTT (0.48) | ALDH1A1HTTLMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0373561-A2 | Heat sensitive recording material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |