SCHEMBL9808166

SCHEMBL9808166

Clc1ccc(SCCOc2ccccc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 4/20 0.69
DRD4 P21917 4/20 0.69
NPC1 O15118 4/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
RAB9A P51151 2/20 0.60
DRD3 P35462 2/20 0.59
AR P10275 3/20 0.51
LMNA P02545 4/20 0.49
ALDH1A1 P00352 3/20 0.49
KCNA3 P22001 1/20 0.48
MAPK1 P28482 2/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
HTT P42858 1/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
PTGDR2 Q9Y5Y4 1/20 0.46
PPARG P37231 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9808023 0.86 ALDH1A1 (0.61) DRD2DRD4NPC1SMN1; SMN2RAB9A
SCHEMBL1445771 0.84 DRD2 (0.75) DRD2DRD4NPC1SMN1; SMN2RAB9A
SCHEMBL4743803 0.83 DRD2 (0.58) DRD2DRD4NPC1SMN1; SMN2RAB9A
SCHEMBL20005618 0.82 DRD2 (0.57) DRD2DRD4NPC1SMN1; SMN2RAB9A
SCHEMBL5824818 0.82 NPC1 (0.57) DRD2DRD4NPC1SMN1; SMN2RAB9A
SCHEMBL10407801 0.81 DRD4 (0.53) DRD2DRD4NPC1SMN1; SMN2RAB9A
SCHEMBL9808032 0.81 DRD2 (0.69) DRD2DRD4NPC1SMN1; SMN2RAB9A
Hydrochloric Acid SCHEMBL8042214 0.81 DRD4 (0.97) DRD2DRD4DRD3ALDH1A1
SCHEMBL20005794 0.80 POLB (0.57) DRD2DRD4NPC1SMN1; SMN2RAB9A
SCHEMBL9770356 0.80 NPC1 (0.63) DRD2DRD4NPC1SMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4985393-A Bis/hydroxyphenylthio/ Compounds KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1991-01-15 US disclosed
EP-0373561-A2 Heat sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-06-20 EP disclosed