Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808116 | 0.84 | LMNA (0.41) | LMNAMAPK1HTTALDH1A1GAA | |
| SCHEMBL9978253 | 0.80 | LMNA (0.47) | LMNAMAPK1HTTALDH1A1GAA | |
| SCHEMBL19996379 | 0.79 | KDM4E (0.39) | LMNAMAPK1HTTALDH1A1GAA | |
| SCHEMBL19996380 | 0.78 | KDM4E (0.41) | LMNAMAPK1HTTALDH1A1GAA | |
| SCHEMBL9988593 | 0.76 | KDM4E (0.45) | LMNAMAPK1HTTALDH1A1GAA | |
| SCHEMBL29825060 | 0.76 | LMNA (0.53) | LMNAMAPK1HTTALDH1A1GAA | |
| SCHEMBL9980397 | 0.76 | KDM4E (0.45) | LMNAMAPK1HTTALDH1A1GAA | |
| SCHEMBL16008090 | 0.76 | LMNA (0.53) | LMNAMAPK1HTTALDH1A1GAA | |
| SCHEMBL9988607 | 0.76 | KDM4E (0.45) | LMNAMAPK1HTTALDH1A1GAA | |
| SCHEMBL683412 | 0.75 | ALDH1A1 (0.42) | LMNAHTTALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0373561-A2 | Heat sensitive recording material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |