Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808186 | 0.84 | LMNA (0.37) | LMNAMAPK1HTTALDH1A1GAA | |
| SCHEMBL9416187 | 0.80 | INPPL1 (0.42) | LMNAMAPK1HTTALDH1A1KDM4E | |
| SCHEMBL9808037 | 0.80 | TDP1 (0.46) | LMNAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL278552 | 0.79 | LMNA (0.42) | LMNAMAPK1HTTALDH1A1GAA | |
| SCHEMBL10458624 | 0.78 | S1PR1 (0.41) | LMNAMAPK1HTTALDH1A1GAA | |
| SCHEMBL11789508 | 0.76 | KDM4E (0.49) | LMNAALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL419937 | 0.74 | THRB (0.41) | MAPK1HTTALDH1A1KDM4EMAPT | |
| SCHEMBL10338882 | 0.73 | ALDH1A1 (0.41) | LMNAMAPK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL7711452 | 0.73 | CYP1A2 (0.41) | LMNAMAPK1HTTALDH1A1GAA | |
| SCHEMBL905336 | 0.72 | KDM4E (0.41) | ALDH1A1GAAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2134287-A | — | — | None | — | — | JP | disclosed |
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0373561-A2 | Heat sensitive recording material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |
| JP-H02134287-A | THERMAL RECORDING MATERIAL | KANZAKI PAPER MFG CO LTD | 1990-05-23 | — | — | JP | disclosed |