Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808192 | 0.95 | LMNA (0.41) | HSP90AA1KCNH2L3MBTL1TDP1ATM | |
| SCHEMBL9808043 | 0.93 | SMN1; SMN2 (0.41) | HSP90AA1KCNH2L3MBTL1TDP1ATM | |
| SCHEMBL9808274 | 0.93 | SMN1; SMN2 (0.41) | HSP90AA1KCNH2L3MBTL1TDP1ATM | |
| SCHEMBL3759191 | 0.90 | HSP90AA1 (0.44) | HSP90AA1KCNH2L3MBTL1TDP1MAPK1 | |
| SCHEMBL9808271 | 0.90 | ALDH1A1 (0.43) | HSP90AA1KCNH2L3MBTL1TDP1LMNA | |
| SCHEMBL9808090 | 0.87 | HTT (0.50) | HSP90AA1KCNH2L3MBTL1TDP1LMNA | |
| SCHEMBL14599314 | 0.83 | TDP1 (0.53) | L3MBTL1TDP1ATMLMNAESR1 | |
| SCHEMBL22435401 | 0.83 | ESR1 (0.46) | HSP90AA1KCNH2TDP1LMNACTDSP1 | |
| SCHEMBL22621337 | 0.83 | HSP90AA1 (0.42) | HSP90AA1KCNH2L3MBTL1TDP1LMNA | |
| SCHEMBL9808202 | 0.83 | APP (0.41) | HSP90AA1L3MBTL1TDP1ATMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0373561-A2 | Heat sensitive recording material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |