Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808274 | 0.96 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAESR1CYP1A2CYP2D6 | |
| SCHEMBL9808192 | 0.95 | LMNA (0.41) | SMN1; SMN2LMNAESR1CYP1A2CYP2D6 | |
| SCHEMBL9808205 | 0.93 | HSP90AA1 (0.42) | SMN1; SMN2LMNAESR1CYP1A2CYP2D6 | |
| SCHEMBL9808271 | 0.93 | ALDH1A1 (0.43) | SMN1; SMN2LMNAESR1TSHRNR1H2 | |
| SCHEMBL3759191 | 0.89 | HSP90AA1 (0.44) | SMN1; SMN2MAPK1L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL14599314 | 0.86 | TDP1 (0.53) | SMN1; SMN2LMNAESR1CYP1A2CYP2D6 | |
| SCHEMBL2302836 | 0.82 | KMT2A (0.50) | SMN1; SMN2LMNAESR1TSHRL3MBTL1 | |
| SCHEMBL9808090 | 0.79 | HTT (0.50) | SMN1; SMN2LMNAESR1CYP1A2CYP2D6 | |
| SCHEMBL6239095 | 0.78 | MAPT (0.54) | SMN1; SMN2LMNACYP1A2MAPK1CYP2C19 | |
| SCHEMBL26246250 | 0.78 | PKM (0.46) | SMN1; SMN2LMNAESR1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |