SCHEMBL9808403

SCHEMBL9808403

CC(C)(Cl)CCC(C)(Cl)CCC(C)(C)Cl

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL740669 0.88 TSHR (0.46) TSHR
SCHEMBL31266934 0.87
SCHEMBL9465341 0.85
SCHEMBL10756606 0.83 TSHR (0.33) TSHR
SCHEMBL31266927 0.83 FDPS (0.33) TSHR
SCHEMBL11049364 0.77 TSHR (0.36) TSHR
SCHEMBL12418599 0.77 TSHR (0.36) TSHR
SCHEMBL8473221 0.74
SCHEMBL4666436 0.72 TSHR (0.39) TSHR
SCHEMBL28713347 0.72 ALDH1A1 (0.67) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0451679-A2 Method of producing polymers NIPPON ZEON CO., LTD. (JP) 1991-10-16 EP disclosed
EP-0224179-B1 PROCESS FOR THE MANUFACTURE OF POLYMERS CONTAINING REACTIVE END GROUPS BAYER AG (DE) 1991-05-15 EP disclosed
EP-0397081-A2 Process for preparation of polymer NIPPON ZEON CO., LTD. (JP) 1990-11-14 EP disclosed
US-4740572-A Process for the production of polymers containing reactive terminal groups BAYER AKTIENGESELLSCHAFT (DE) 1988-04-26 US disclosed
EP-0224759-A2 Manufacture of polymers by cationic polymerization BAYER AG (DE) 1987-06-10 EP disclosed
EP-0224179-A2 Process for the manufacture of polymers containing reactive end groups BAYER AG (DE) 1987-06-03 EP disclosed
US-4611037-A HALOGEN END GROUPS BAYER AKTIENGESELLSCHAFT (DE) 1986-09-09 US disclosed
EP-0175122-A2 Process for the manufacture of polymers containing reactive end groups BAYER AG (DE) 1986-03-26 EP disclosed