⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4673059 | 0.76 | — | — | |
| SCHEMBL2105796 | 0.76 | — | — | |
| SCHEMBL27622214 | 0.76 | — | — | |
| SCHEMBL6219081 | 0.72 | — | — | |
| SCHEMBL3082774 | 0.72 | — | — | |
| SCHEMBL3277597 | 0.72 | ADRA2A (0.33) | — | |
| SCHEMBL10564826 | 0.70 | ALDH1A1 (0.39) | — | |
| SCHEMBL10564171 | 0.70 | MMP1 (0.41) | — | |
| SCHEMBL27806702 | 0.70 | MEN1 (0.38) | — | |
| SCHEMBL243060 | 0.69 | ADRA2A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230347-B1 | MACROLIDE COMPOUNDS, THEIR PREPARATION AND USE | Sankyo Company Limited (JP) | 1991-05-15 | — | — | EP | claimed |
| US-4912090-A | Antiparasitic milbemycin and avermectin derivatives | SANKYO COMPANY LIMITED (JP) | 1990-03-27 | — | — | US | claimed |
| EP-0230347-A1 | Macrolide compounds, their preparation and use | Sankyo Company Limited (JP) | 1987-07-29 | — | — | EP | claimed |
| EP-0230347-B1 | MACROLIDE COMPOUNDS, THEIR PREPARATION AND USE | Sankyo Company Limited (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-4912090-A | Antiparasitic milbemycin and avermectin derivatives | SANKYO COMPANY LIMITED (JP) | 1990-03-27 | — | — | US | disclosed |
| EP-0230347-A1 | Macrolide compounds, their preparation and use | Sankyo Company Limited (JP) | 1987-07-29 | — | — | EP | disclosed |