Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.69 |
| ▸ | RARG | P13631 | 1/20 | 0.69 |
| ▸ | GRM5 | P41594 | 12/20 | 0.54 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983698 | 0.84 | GRM5 (0.52) | RARBRARGGRM5CYP26A1CYP3A4 | |
| SCHEMBL9425762 | 0.83 | RARB (1.00) | RARBRARGSRD5A2NR4A2RXRA | |
| SCHEMBL8960507 | 0.82 | RARB (0.55) | RARBRARGGRM5CYP3A4EPHX2 | |
| SCHEMBL7527125 | 0.82 | GRM5 (0.77) | GRM5CYP26A1CYP3A4 | |
| SCHEMBL24230073 | 0.78 | GRM5 (0.54) | RARBRARGGRM5CYP26A1CYP3A4 | |
| SCHEMBL9808768 | 0.77 | GRM5 (0.48) | RARBRARGGRM5CYP26A1CYP3A4 | |
| SCHEMBL4081970 | 0.77 | P4HA1 (0.47) | RARBRARGGRM5CYP26A1CYP3A4 | |
| SCHEMBL16673635 | 0.76 | P4HA1 (0.46) | RARBRARGGRM5CYP26A1CYP3A4 | |
| SCHEMBL565225 | 0.75 | P4HA1 (0.52) | GRM5CYP26A1CYP3A4 | |
| SCHEMBL24230047 | 0.75 | GRM5 (0.54) | RARBRARGGRM5CYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013744-A | Skin disorders | ALLERGAN, INC. (US) | 1991-05-07 | — | — | US | disclosed |