Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 11/20 | 0.48 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 6/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960230 | 0.87 | CYP3A4 (0.52) | GRM5CYP3A4ACACBRARBRARG | |
| SCHEMBL9425314 | 0.86 | RARB (0.54) | CYP26A1CYP3A4ACACBRARBRARG | |
| SCHEMBL9808757 | 0.77 | RARB (0.69) | GRM5CYP26A1CYP3A4RARBRARG | |
| SCHEMBL9426163 | 0.74 | CA12 (0.45) | CYP3A4 | |
| SCHEMBL7527125 | 0.74 | GRM5 (0.77) | GRM5CYP26A1CYP3A4 | |
| SCHEMBL24230073 | 0.70 | GRM5 (0.54) | GRM5CYP26A1CYP3A4ACACBRARB | |
| SCHEMBL4081970 | 0.70 | P4HA1 (0.47) | GRM5CYP26A1CYP3A4RARBRARG | |
| SCHEMBL8983744 | 0.69 | ACACB (0.32) | ACACB | |
| SCHEMBL16673635 | 0.69 | P4HA1 (0.46) | GRM5CYP26A1CYP3A4RARBRARG | |
| SCHEMBL8983698 | 0.68 | GRM5 (0.52) | GRM5CYP26A1CYP3A4RARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013744-A | Skin disorders | ALLERGAN, INC. (US) | 1991-05-07 | — | — | US | disclosed |