Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 6/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452553 | 0.86 | DHFR (0.47) | DHFRTSHRMAPTALDH1A1MEN1 | |
| SCHEMBL9808906 | 0.84 | TSHR (0.60) | TSHRCYP3A4MAPTALDH1A1MEN1 | |
| SCHEMBL10509379 | 0.84 | DHFR (0.45) | DHFRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10451414 | 0.83 | DHFR (0.43) | DHFRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9808938 | 0.83 | ALDH1A1 (0.50) | DHFRCYP3A4MAPTALDH1A1MEN1 | |
| SCHEMBL1901253 | 0.81 | VCAM1 (0.53) | DHFRTSHRCYP3A4MAPTALDH1A1 | |
| SCHEMBL9808925 | 0.77 | ALKBH3 (0.36) | TSHRCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL84100 | 0.77 | TSHR (0.67) | TSHRCYP3A4MAPTALDH1A1MEN1 | |
| SCHEMBL30753177 | 0.77 | TSHR (0.67) | TSHRCYP3A4MAPTALDH1A1MEN1 | |
| Ammonia Solution, Strong SCHEMBL28193869 | 0.76 | TSHR (0.64) | TSHRCYP3A4MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985463-A | Aminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-01-15 | — | — | US | disclosed |
| US-4956007-A | Nitraminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYOR RT. (HU) | 1990-09-11 | — | — | US | disclosed |
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |