Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809097 | 0.89 | GSK3A (0.40) | GSK3AGSK3BMAPTALDH1A1KDM4E | |
| SCHEMBL9809100 | 0.85 | MAPT (0.38) | GSK3AGSK3BMAPTALDH1A1KDM4E | |
| SCHEMBL11611721 | 0.84 | GSK3A (0.45) | GSK3AGSK3BMAPTALDH1A1KDM4E | |
| SCHEMBL9809065 | 0.74 | ALOX15 (0.62) | MAPTALDH1A1KDM4EPOLBGAA | |
| SCHEMBL9809091 | 0.70 | HTR3E (0.41) | MAPTALDH1A1GAABCHEPTGS2 | |
| SCHEMBL3527177 | 0.68 | ALDH1A1 (0.41) | GSK3AGSK3BMAPTALDH1A1KDM4E | |
| SCHEMBL3533226 | 0.67 | ALDH1A1 (0.40) | GSK3AGSK3BMAPTALDH1A1KDM4E | |
| SCHEMBL11619799 | 0.67 | GSK3A (0.43) | GSK3AGSK3BMAPTALDH1A1KDM4E | |
| SCHEMBL9809075 | 0.66 | BCHE (0.47) | MAPTALDH1A1KDM4EPOLBGLA | |
| SCHEMBL28883352 | 0.64 | POLB (0.70) | GSK3AGSK3BMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063245-A | Hormone inhibitors | NOVA PHARMACEUTICAL CORPORATION (US) | 1991-11-05 | — | — | US | disclosed |