Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809117 | 0.80 | CYP19A1 (0.45) | ALDH1A1KDM4EHSD17B10CYP19A1SMN1; SMN2 | |
| SCHEMBL3882745 | 0.73 | CYP19A1 (0.56) | ALDH1A1KDM4ECYP19A1SMN1; SMN2MAOA | |
| SCHEMBL9809063 | 0.72 | BCHE (0.49) | ALDH1A1KDM4ECYP19A1SMN1; SMN2TDP1 | |
| SCHEMBL536896 | 0.72 | CYP19A1 (0.55) | ALDH1A1KDM4ECYP19A1SMN1; SMN2MAOA | |
| SCHEMBL4335032 | 0.69 | SMN1; SMN2 (0.55) | ALDH1A1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL4320070 | 0.68 | ALDH1A1 (0.56) | ALDH1A1KDM4ESMN1; SMN2HTTGAA | |
| SCHEMBL4324271 | 0.68 | ALDH1A1 (0.48) | ALDH1A1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL680891 | 0.67 | LMNA (0.42) | ALDH1A1HSD17B10SMN1; SMN2HTTLMNA | |
| SCHEMBL4324537 | 0.67 | SMN1; SMN2 (0.53) | ALDH1A1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL8260565 | 0.66 | BCHE (0.42) | ALDH1A1KDM4EHSD17B10SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063245-A | Hormone inhibitors | NOVA PHARMACEUTICAL CORPORATION (US) | 1991-11-05 | — | — | US | disclosed |