Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | CASP6 | P55212 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10772754 | 0.82 | POLB (0.47) | ALDH1A1MAPTPOLBGAACASP6 | |
| SCHEMBL10600156 | 0.78 | CCR2 (0.41) | APEX1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL9809133 | 0.78 | APEX1 (0.42) | APEX1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL9711529 | 0.78 | RAPGEF4 (0.58) | APEX1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL10691724 | 0.77 | APEX1 (0.39) | APEX1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL9878782 | 0.75 | RAPGEF4 (0.41) | APEX1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL10900096 | 0.75 | CA2 (0.40) | APEX1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL9809126 | 0.74 | RECQL (0.40) | APEX1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL10595422 | 0.74 | CA2 (0.40) | APEX1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL10633547 | 0.72 | KDM4E (0.41) | APEX1ALDH1A1KDM4EMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199056-B1 | PROCESS FOR THE MANUFACTURE OF TRIPHENODIOXAZINES | BAYER AG (DE) | 1991-05-22 | — | — | EP | disclosed |
| EP-0199056-A2 | Process for the manufacture of triphenodioxazines | BAYER AG (DE) | 1986-10-29 | — | — | EP | disclosed |