Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | ECE1 | P42892 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL10435217 | 0.92 | MEN1 (0.51) | HDAC1HDAC6RAB9AALDH1A1LMNA | |
| SCHEMBL24267375 | 0.87 | ECE1 (0.60) | HDAC1HDAC6RAB9AALDH1A1LMNA | |
| SCHEMBL29995369 | 0.87 | ECE1 (0.60) | HDAC1HDAC6RAB9AALDH1A1LMNA | |
| SCHEMBL21467402 | 0.86 | LMNA (0.67) | HDAC1HDAC6RAB9AALDH1A1LMNA | |
| SCHEMBL24567733 | 0.86 | LMNA (0.67) | HDAC1HDAC6RAB9AALDH1A1LMNA | |
| SCHEMBL28152984 | 0.84 | SMN1; SMN2 (0.54) | HDAC1HDAC6RAB9AALDH1A1LMNA | |
| SCHEMBL16322351 | 0.83 | ECE1 (0.56) | HDAC1HDAC6RAB9AALDH1A1LMNA | |
| SCHEMBL8221634 | 0.83 | GPR132 (0.64) | HDAC1HDAC6RAB9AALDH1A1LMNA | |
| SCHEMBL28865879 | 0.83 | ECE1 (0.56) | HDAC1HDAC6RAB9AALDH1A1LMNA | |
| SCHEMBL1106964 | 0.81 | HDAC1 (0.62) | HDAC1HDAC6RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376185-A2 | Process for purification of 1,2-bis(nicotinamido)propane | Chugai Seiyaku Kabushiki Kaisha (JP) | 1990-07-04 | — | — | EP | claimed |
| CN-112226197-B | Modified silicone sealant for treating asphalt pavement cracks and preparation method thereof | 重庆重交再生资源开发股份有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-112226197-A | Modified silicone sealant for treating asphalt pavement cracks and preparation method thereof | 重庆重交再生资源开发股份有限公司 | 2021-01-15 | — | — | CN | disclosed |
| EP-0376185-A3 | PROCESS FOR PURIFICATION OF 1,2-BIS(NICOTINAMIDO)PROPANE | Chugai Seiyaku Kabushiki Kaisha (JP) | 1991-03-27 | — | — | EP | disclosed |
| EP-0376185-A2 | Process for purification of 1,2-bis(nicotinamido)propane | Chugai Seiyaku Kabushiki Kaisha (JP) | 1990-07-04 | — | — | EP | disclosed |
| EP-0376185-A2 | Process for purification of 1,2-bis(nicotinamido)propane | Chugai Seiyaku Kabushiki Kaisha (JP) | 1990-07-04 | — | — | EP | disclosed |