Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16322351 | 1.00 | ECE1 (0.56) | ECE1THRBRAB9AALDH1A1LMNA | |
| SCHEMBL29995369 | 0.92 | ECE1 (0.60) | ECE1THRBRAB9AALDH1A1LMNA | |
| SCHEMBL24267375 | 0.92 | ECE1 (0.60) | ECE1THRBRAB9AALDH1A1LMNA | |
| SCHEMBL13724316 | 0.91 | THRB (0.63) | ECE1THRBRAB9AALDH1A1LMNA | |
| SCHEMBL29421299 | 0.89 | LMNA (0.54) | ECE1THRBRAB9AALDH1A1LMNA | |
| SCHEMBL24298437 | 0.86 | LMNA (0.54) | ECE1THRBRAB9AALDH1A1LMNA | |
| SCHEMBL9809554 | 0.83 | HDAC1 (0.57) | ECE1THRBRAB9AALDH1A1LMNA | |
| SCHEMBL24567733 | 0.82 | LMNA (0.67) | ECE1THRBRAB9AALDH1A1LMNA | |
| SCHEMBL21467402 | 0.82 | LMNA (0.67) | ECE1THRBRAB9AALDH1A1LMNA | |
| SCHEMBL30557508 | 0.82 | LMNA (0.67) | ECE1THRBRAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132950-B | Aminopyridines and methods of use | 麦迪威森技术有限责任公司 | 2018-11-09 | — | — | CN | disclosed |