SCHEMBL9809679

SCHEMBL9809679

C(=NNc1ccccc1Cc1ccccc1)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GRK2 P25098 1/20 0.51
NOX1 Q9Y5S8 1/20 0.50
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
RAB9A P51151 4/20 0.49
NPC1 O15118 2/20 0.49
MAPT P10636 5/20 0.43
ALDH1A1 P00352 4/20 0.43
LMNA P02545 4/20 0.43
GAA P10253 3/20 0.43
KDM4E B2RXH2 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HPGD P15428 2/20 0.41
HTR2A P28223 1/20 0.41
DDX3X O00571 1/20 0.41
TAAR1 Q96RJ0 1/20 0.40
DRD3 P35462 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27780737 0.90 GRK2 (0.65) GRK2MEN1KMT2ARAB9ANPC1
SCHEMBL15782676 0.75 L3MBTL1 (0.47) GRK2MEN1KMT2AALDH1A1LMNA
SCHEMBL5429720 0.75 RAB9A (0.57) NOX1MEN1KMT2ARAB9ANPC1
SCHEMBL11574435 0.72 MEN1 (0.55) NOX1MEN1KMT2ARAB9ANPC1
SCHEMBL27620900 0.72 L3MBTL1 (0.55) LMNAGAAL3MBTL1HTR2ADRD3
SCHEMBL6369254 0.70 LMNA (0.45) GRK2MEN1KMT2ARAB9AMAPT
SCHEMBL4575540 0.70 L3MBTL1 (0.58) MAPTALDH1A1LMNAKDM4ETDP1
SCHEMBL14582040 0.70 RAB9A (0.51) GRK2MEN1KMT2ARAB9ANPC1
SCHEMBL11433940 0.69 NOX1 (0.53) NOX1MEN1KMT2ARAB9ANPC1
SCHEMBL27439587 0.69 NOX1 (0.53) NOX1MEN1KMT2ARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE33719-E Sweetened edible formulations BIOSPHERICS INCORPORATED (US) 1991-10-15 US disclosed
US-4262032-A L-HEXOSE MONOSACCHARIDES BIOSPHERICS INCORPORATED (US) 1981-04-14 US disclosed