SCHEMBL9809705

SCHEMBL9809705

CCc1ccccc1C(C)OP(=O)(S)S

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.36
MAPT P10636 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 4/20 0.35
ADRA2A P08913 2/20 0.35
ADRA2B P18089 2/20 0.35
ADRA2C P18825 2/20 0.35
POLB P06746 2/20 0.34
CYP3A4 P08684 1/20 0.33
KDM4E B2RXH2 1/20 0.33
KMT2A Q03164 1/20 0.33
GABRA1 P14867 2/20 0.32
GABRB2 P47870 2/20 0.32
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15127472 0.79 MAPT (0.39) L3MBTL1MAPTNPSR1ADRA2AADRA2B
SCHEMBL8750403 0.79 MAPT (0.41) L3MBTL1MAPTNPSR1ALDH1A1ADRA2A
SCHEMBL4623382 0.78 GABRA1 (0.34) L3MBTL1MAPTNPSR1CYP3A4KMT2A
SCHEMBL10335458 0.77 ADRA2A (0.33) L3MBTL1MAPTNPSR1ALDH1A1ADRA2A
SCHEMBL18946175 0.77 GABRA1 (0.39) L3MBTL1MAPTNPSR1ALDH1A1POLB
SCHEMBL705287 0.76 MAPT (0.39) L3MBTL1MAPTNPSR1ADRA2AADRA2B
SCHEMBL11786791 0.76 GABRA1 (0.40) L3MBTL1MAPTNPSR1ALDH1A1ADRA2A
SCHEMBL11425704 0.75 ACP3 (0.38) ALDH1A1CYP3A4GABRA1GABRB2TSHR
SCHEMBL14650862 0.74 GABRA1 (0.41) L3MBTL1MAPTNPSR1ADRA2AADRA2B
SCHEMBL545484 0.72 GABRA1 (0.46) L3MBTL1MAPTNPSR1CYP3A4GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0145846-B1 POLYHDROXY POLYMER DELIVERY SYSTEM ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) 1991-06-12 EP claimed
EP-0007544-B1 THIENYL-DITHIOPHOSPHORIC ACID ESTERS, PROCESS FOR THEIR PREPARATION, THEIR USE AS PESTICIDES, PROCESS FOR THEIR PREPARATION AND METHOD FOR COMBATING PESTS BASF Aktiengesellschaft (DE) 1981-09-02 EP disclosed
EP-0008098-B1 1-PHENYL-3,3-DICHLORO-2-PROPENYL-(DI)(THIO)-PHOSPHORIC ACID ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES BASF Aktiengesellschaft (DE) 1981-08-26 EP disclosed
EP-0008768-A1 Aroyl ureas, process for their preparation and their use in insecticidal and acaricidal compositions BASF Aktiengesellschaft (DE) 1980-03-19 EP disclosed
US-4172146-A Substituted phenyl derivatives CIBA-GEIGY CORPORATION (US) 1979-10-23 US disclosed
US-4145439-A NEMATOCIDES, FUNGICIDES, BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-03-20 US disclosed
US-4069344-A INSECTICIDAL SUBSTITUTED PHENYL DERIVATIVES CIBA-GEIGY CORPORATION (US) 1978-01-17 US disclosed
US-4067972-A PESTICIDES CIBA-GEIGY CORPORATION (US) 1978-01-10 US disclosed
US-4035488-A Insecticidal and acaricidal substituted phenyl thiophosphoric acid esters CIBA-GEIGY CORPORATION (US) 1977-07-12 US disclosed
US-4017563-A INSECTICIDES, REDUCED TOXICITY TO MAMMALS CIBA-GEIGY AG (CH) 1977-04-12 US disclosed
US-3973010-A Insecticidal and acaricidal composition and method with triazolyl phosphoric esters acid CIBA-GEIGY CORPORATION (US) 1976-08-03 US disclosed
US-3969444-A PESTICIDE CIBA-GEIGY AG (CH) 1976-07-13 US disclosed
US-3969517-A INSECTICIDE, MITICIDE CIBA-GEIGY AG (CH) 1976-07-13 US disclosed
US-3969438-A PESTICIDE CIBA-GEIGY AG (CH) 1976-07-13 US disclosed
US-3966921-A NEMATOCIDES CIBA-GEIGY CORPORATION (US) 1976-06-29 US disclosed
US-3960947-A FORMAMIDINE COMPOUNDS, PESTICIDES CIBA-GEIGY CORPORATION (US) 1976-06-01 US disclosed
US-3956306-A PESTICIDES CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed
US-3948940-A Pesticidal phthalimido phosphorous ester compounds CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed
US-3934010-A MITICIDE CIBA-GEIGY CORPORATION (US) 1976-01-20 US disclosed
US-3932629-A Triazolyl phosphorus esters as pesticides CIBA-GEIGY CORPORATION (US) 1976-01-13 US disclosed