Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.46 |
| ▸ | MAOB | P27338 | 9/20 | 0.44 |
| ▸ | MAOA | P21397 | 5/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9143963 | 0.82 | DRD3 (0.46) | ACHEMAOBKMT2AALDH1A1DRD2 | |
| SCHEMBL7386417 | 0.80 | ALDH1A1 (0.46) | NPC1MITFRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL13438368 | 0.78 | TSHR (0.39) | MAOBBCHEKMT2AKDM4EDRD2 | |
| SCHEMBL6947117 | 0.78 | TSHR (0.41) | MAOBNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL8980599 | 0.78 | TSHR (0.41) | MAOBHTTKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL8639215 | 0.78 | TSHR (0.41) | MAOBKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL8980560 | 0.78 | PKM (0.36) | MAOBL3MBTL1KDM4E | |
| SCHEMBL13063351 | 0.77 | PKM (0.38) | BCHEDRD2DRD3 | |
| Oxalic Acid SCHEMBL9140831 | 0.77 | DRD3 (0.42) | ACHEPOLBHTTKMT2AALDH1A1 | |
| SCHEMBL8578943 | 0.75 | PRMT5 (0.39) | NPC1HTTRAB9AKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071850-A | Cardiovascular disorders | PIERRE FABRE MEDICAMENT (FR) | 1991-12-10 | — | — | US | disclosed |