Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 14/20 | 0.46 |
| ▸ | CA2 | P00918 | 14/20 | 0.46 |
| ▸ | CA9 | Q16790 | 11/20 | 0.46 |
| ▸ | CA12 | O43570 | 7/20 | 0.42 |
| ▸ | CA7 | P43166 | 5/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17350894 | 0.73 | CA1 (0.48) | CA1CA2CA9CA12CA7 | |
| SCHEMBL4024315 | 0.67 | CA1 (0.53) | CA1CA2CA9CA12CA7 | |
| SCHEMBL5625166 | 0.65 | CA1 (0.56) | CA1CA2CA9CA12CA7 | |
| SCHEMBL17350895 | 0.64 | CA1 (0.57) | CA1CA2CA9CA12CA7 | |
| SCHEMBL8024515 | 0.63 | CA2 (1.00) | CA1CA2CA9CA12CA7 | |
| SCHEMBL17395951 | 0.62 | CA1 (0.50) | CA1CA2CA9CA12CA7 | |
| SCHEMBL210441 | 0.62 | CA1 (0.34) | CA1CA2CA9CA12CA7 | |
| SCHEMBL209432 | 0.62 | CHEK1 (0.36) | CA1CA2CA9CA12CA7 | |
| SCHEMBL28174280 | 0.61 | PNMT (0.50) | CA1CA2CA9CA12CA7 | |
| SCHEMBL6297784 | 0.61 | CA2 (0.82) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017567-A | Steroid antiinflammatory | SCHERING CORPORATION (US) | 1991-05-21 | — | — | US | disclosed |