SCHEMBL9810360

SCHEMBL9810360

CCCOC(=O)C1CCC(O)(c2ccc(C)cc2)CC1

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
HTR2C P28335 1/20 0.40
TSHR P16473 1/20 0.40
LMNA P02545 2/20 0.39
POLB P06746 1/20 0.39
OPRM1 P35372 1/20 0.39
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9810614 0.92 ALDH1A1 (0.41) ALDH1A1HTR2CTSHRLMNAPOLB
SCHEMBL9810272 0.91 PPARG (0.41) ALDH1A1HTR2CTSHRLMNA
SCHEMBL9810581 0.90 ALDH1A1 (0.51) ALDH1A1HTR2CTSHRLMNAPOLB
SCHEMBL9810689 0.90 PPARG (0.43) ALDH1A1HTR2CTSHRLMNA
SCHEMBL9810322 0.90 PPARG (0.43) ALDH1A1HTR2CTSHRLMNA
SCHEMBL9810416 0.90 PPARG (0.43) ALDH1A1HTR2CTSHRLMNA
SCHEMBL9810568 0.88 LMNA (0.43) ALDH1A1LMNAOPRM1
SCHEMBL9810492 0.87 ATM (0.42) ALDH1A1LMNAOPRM1
SCHEMBL9810386 0.87 OPRL1 (0.43) ALDH1A1OPRM1
SCHEMBL9810626 0.87 TSHR (0.50) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5068389-A TERTIARY ALCOHOLS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-11-26 US disclosed