Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810508 | 0.92 | L3MBTL1 (0.41) | LMNAL3MBTL1NPC1OPRM1OPRD1 | |
| SCHEMBL9810267 | 0.91 | LMNA (0.40) | LMNAL3MBTL1NPC1OPRM1OPRD1 | |
| SCHEMBL9810386 | 0.91 | OPRL1 (0.43) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL9810345 | 0.90 | PPARG (0.42) | LMNAL3MBTL1NPC1ALDH1A1MAPT | |
| SCHEMBL9810335 | 0.90 | PPARG (0.42) | LMNAL3MBTL1NPC1ALDH1A1MAPT | |
| SCHEMBL9810450 | 0.90 | PPARG (0.42) | LMNAL3MBTL1NPC1ALDH1A1MAPT | |
| SCHEMBL9810410 | 0.89 | LMNA (0.53) | LMNAL3MBTL1NPC1OPRM1OPRD1 | |
| SCHEMBL9810349 | 0.89 | OPRL1 (0.45) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL9810360 | 0.88 | ALDH1A1 (0.42) | LMNAOPRM1ALDH1A1 | |
| SCHEMBL9810555 | 0.88 | THRA (0.42) | OPRL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068389-A | TERTIARY ALCOHOLS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |