Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.74 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5493620 | 0.85 | ALOX15 (1.00) | LMNAMAPTALOX15HSD17B10MEN1 | |
| SCHEMBL11663696 | 0.83 | ALOX15 (0.58) | LMNAMAPTALOX15HSD17B10MEN1 | |
| SCHEMBL10750244 | 0.81 | ALOX15 (0.68) | LMNAMAPTALOX15HSD17B10MEN1 | |
| SCHEMBL27884492 | 0.81 | ALOX15 (0.68) | LMNAMAPTALOX15HSD17B10MEN1 | |
| SCHEMBL926861 | 0.80 | ALOX15 (0.48) | LMNAMAPTALOX15HSD17B10MEN1 | |
| SCHEMBL5179232 | 0.78 | MCL1 (0.53) | LMNAMAPTALOX15HSD17B10MEN1 | |
| SCHEMBL3847009 | 0.76 | MEN1 (0.45) | LMNAMAPTALOX15HSD17B10MEN1 | |
| SCHEMBL1116671 | 0.76 | HSD17B10 (0.68) | LMNAMAPTALOX15HSD17B10MEN1 | |
| SCHEMBL9759553 | 0.76 | PDE10A (0.52) | LMNAMAPTALOX15HSD17B10MEN1 | |
| SCHEMBL3409348 | 0.76 | LMNA (0.61) | LMNAMAPTALOX15HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169662-B1 | SUBSTITUTED VINYL- AND ALKINYL-CYANOCYCLOALKANOLS AND VINYL- AND ALKINYL-CYANOHETEROCYCLOALKANOLS AS AGENTS TO COMBAT ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2018-07-11 | — | — | EP | disclosed |
| US-9388140-B2 | Substituted benzimidazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-07-12 | — | — | US | disclosed |
| US-20140302010-A1 | SUBSTITUTED BENZIMIDAZOLES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-09 | — | — | US | disclosed |
| EP-0452302-A1 | PREPARATION ON ORTHO-(ALKYL- OR ARYLTHIO)PHENOLS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-23 | — | — | EP | disclosed |
| WO-1990005718-A1 | PREPARATION ON ORTHO-(ALKYL- OR ARYLTHIO)PHENOLS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-05-31 | — | — | WO | disclosed |
| EP-0369074-A1 | Preparation of ortho-(alkyl-or arylthio) phenols | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-05-23 | — | — | EP | disclosed |
| US-4792633-A | REACTING PHENOLS AND DISULFIDES USING ALUMINUM SILICATE CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0156352-B1 | PREPARATION OF (ALKYLTHIO-,CYCLOALKYTHIO- OR ARYLTHIO)-PHENOLS | ETHYL CORPORATION (US) | 1988-08-03 | — | — | EP | disclosed |
| US-4547593-A | REDISTRIBUTION OF HYDROCARBYLTHIO GROUPS; ALUMINUM PHENOXIDE CATALYST | ETHYL CORPORATION (US) | 1985-10-15 | — | — | US | disclosed |
| EP-0156352-A2 | Preparation of (alkylthio-,cycloalkythio- or arylthio)-phenols | ETHYL CORPORATION (US) | 1985-10-02 | — | — | EP | disclosed |
| US-RE31771-E | REACTING AN ORTHO-UNSUBSTITUTED PHENOL AND A DISULFIDE USING AN ALUMINUM PHENOXIDE CATALYST | ETHYL CORPORATION (US) | 1984-12-18 | — | — | US | disclosed |
| US-4324920-A | REACTION OF A PHENOL WITH A HYDROCARBYL DISULFIDE IN THE PRESENCE OF AN ALUMINUM PHENOXIDE | ETHYL CORPORATION (US) | 1982-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140302010-A1 | SUBSTITUTED BENZIMIDAZOLES | CCNI, MKI67, CCND2 | LMNA 1755/4885MAPT 3123/4885ALOX15 2060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.