SCHEMBL5179232

SCHEMBL5179232

CSc1ccc(O)c(SC)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.53
HSD17B10 Q99714 6/20 0.46
KMT2A Q03164 4/20 0.46
ALOX15 P16050 4/20 0.46
MEN1 O00255 3/20 0.46
HPGD P15428 3/20 0.46
LMNA P02545 2/20 0.46
TP53 P04637 2/20 0.46
MAPT P10636 2/20 0.46
ALOX12 P18054 2/20 0.46
GAA P10253 1/20 0.46
ALDH1A1 P00352 4/20 0.37
HTT P42858 3/20 0.37
PLA2G1B P04054 1/20 0.37
HSP90AA1 P07900 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
HIF1A Q16665 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5181271 0.81 MCL1 (0.48) MCL1HSD17B10KMT2AALOX15MEN1
SCHEMBL2122382 0.80 MCL1 (0.57) MCL1HSD17B10KMT2AALOX15MEN1
SCHEMBL9810679 0.78 LMNA (0.74) HSD17B10KMT2AALOX15MEN1HPGD
SCHEMBL926861 0.78 ALOX15 (0.48) MCL1HSD17B10KMT2AALOX15MEN1
SCHEMBL29144903 0.77 MCL1 (0.39) MCL1HSD17B10HPGDMAPTGAA
SCHEMBL2912899 0.76 MCL1 (0.53) MCL1HSD17B10KMT2AALOX15MEN1
SCHEMBL4544572 0.76 ALDH1A1 (0.54) MCL1HSD17B10KMT2AALOX15MEN1
SCHEMBL27530049 0.76 MCL1 (0.53) MCL1HSD17B10KMT2AALOX15MEN1
SCHEMBL9199758 0.74 MCL1 (0.52) MCL1HSD17B10KMT2AALOX15MEN1
SCHEMBL9525070 0.74 MCL1 (0.52) MCL1HSD17B10KMT2AALOX15HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122012006-A Ultraviolet curing glue with high adhesion performance and preparation method thereof 浙江至格科技有限公司 2026-05-12 CN disclosed
CN-118209645-A Method for detecting 2, 4-dimethylbenzene thiophenol related substances 重庆药友制药有限责任公司 2024-06-18 CN disclosed
EP-2570418-A2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-03-20 EP disclosed
EP-1555267-B1 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES OTSUKA PHARMA CO LTD (JP) 2013-01-16 EP disclosed
US-7262212-B2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-08-28 US disclosed
EP-1057808-B1 Sulfur-containing unsaturated carboxylate compound and its use MITSUI CHEMICALS INC (JP) 2007-03-14 EP disclosed
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-05-04 US disclosed
EP-1555267-A1 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-07-20 EP disclosed
US-6458908-B1 A PROCESS FOR PREPARING A SULFUR-CONTAINING UNSATURATED CARBOXYLATE COMPOUND AS CLAIMED IN CLAIM 1 COMPRISING REACTING A SULFUR-CONTAINING DERIVATIVE FOR OPTICAL POLYMERS MITSUI CHEMICALS, INC. (JP) 2002-10-01 US disclosed
EP-1057808-A2 Sulfur-containing unsaturated carboxylate compound and its use Mitsui Chemicals, Inc. (JP) 2000-12-06 EP disclosed
WO-1984004092-A1 (HYDROCARBYLTHIO)PHENOLS AND THEIR PREPARATION ETHYL CORP (US) 1984-10-25 WO disclosed
EP-0122203-A1 (Hydrocarbylthio)phenols and their preparation ETHYL CORPORATION (US) 1984-10-17 EP disclosed
US-3989721-A Disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-11-02 US disclosed
US-3989720-A Disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-11-02 US disclosed
US-3988352-A Disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-10-26 US disclosed
US-3979414-A Disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-09-07 US disclosed
US-3965115-A Disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-06-22 US disclosed
US-3963753-A Disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-06-15 US disclosed
US-3963752-A Disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-06-15 US disclosed
US-3951618-A Method of use of, and compositions containing, disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles NR2C2, NR4A3, NR4A2 MCL1 3401/4885HSD17B10 467/4885KMT2A 4267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.