SCHEMBL9810685

SCHEMBL9810685

CCCCCSc1cccc(O)c1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.44
ESR2 Q92731 2/20 0.44
MAP1LC3B Q9GZQ8 1/20 0.43
MAP1LC3A Q9H492 1/20 0.43
OPRM1 P35372 3/20 0.41
DRD2 P14416 2/20 0.41
DRD3 P35462 2/20 0.41
OPRD1 P41143 2/20 0.41
OPRK1 P41145 2/20 0.41
ACHE P22303 3/20 0.41
TSHR P16473 1/20 0.41
P4HB P07237 1/20 0.40
THRB P10828 2/20 0.40
PLK1 P53350 1/20 0.40
BLM P54132 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
THRA P10827 1/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19194627 0.98 ESR1 (0.46) ESR1ESR2MAP1LC3BMAP1LC3AOPRM1
SCHEMBL19195086 0.98 ESR1 (0.46) ESR1ESR2MAP1LC3BMAP1LC3AOPRM1
SCHEMBL8757169 0.98 ESR1 (0.46) ESR1ESR2MAP1LC3BMAP1LC3AOPRM1
SCHEMBL7735444 0.98 ESR1 (0.46) ESR1ESR2MAP1LC3BMAP1LC3AOPRM1
SCHEMBL9323120 0.95 MAP1LC3B (0.46) ESR1ESR2MAP1LC3BMAP1LC3AOPRM1
SCHEMBL19194628 0.92 ESR1 (0.51) ESR1ESR2MAP1LC3BMAP1LC3AOPRM1
Resorcinol SCHEMBL27620430 0.84 ALDH1A1 (0.47) MAP1LC3BMAP1LC3AOPRM1DRD2DRD3
SCHEMBL8079236 0.81 CA2 (0.42) MAP1LC3BMAP1LC3AOPRM1ACHETSHR
SCHEMBL29650290 0.80 ALDH1A1 (0.39) OPRM1ACHETSHR
SCHEMBL19692896 0.80 ALDH1A1 (0.39) OPRM1ACHETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0452302-A1 PREPARATION ON ORTHO-(ALKYL- OR ARYLTHIO)PHENOLS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-23 EP disclosed
WO-1990005718-A1 PREPARATION ON ORTHO-(ALKYL- OR ARYLTHIO)PHENOLS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-05-31 WO disclosed