Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 1/20 | 0.50 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810782 | 0.87 | PYGM (0.46) | PYGMP2RY2 | |
| SCHEMBL9780784 | 0.84 | — | — | |
| SCHEMBL9780774 | 0.84 | — | — | |
| SCHEMBL9810767 | 0.83 | PYGM (0.48) | PYGM | |
| SCHEMBL9810807 | 0.81 | P2RY2 (0.49) | PYGMP2RY2P2RY6 | |
| SCHEMBL9810750 | 0.79 | PYGM (0.51) | PYGMP2RY2P2RY6 | |
| SCHEMBL9810761 | 0.79 | PYGM (0.42) | PYGMP2RY2 | |
| SCHEMBL9810803 | 0.79 | KDM4E (0.44) | PYGMP2RY2 | |
| SCHEMBL9643485 | 0.78 | P2RY2 (0.48) | PYGMP2RY2 | |
| SCHEMBL9810756 | 0.78 | P2RY2 (0.45) | PYGMP2RY2P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257378-B1 | PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1991-07-03 | — | — | EP | claimed |
| EP-0257378-B1 | PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1991-07-03 | — | — | EP | disclosed |