Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810782 | 0.86 | PYGM (0.46) | PYGM | |
| SCHEMBL9780751 | 0.84 | — | — | |
| SCHEMBL9780739 | 0.84 | — | — | |
| SCHEMBL9810754 | 0.83 | PYGM (0.50) | PYGM | |
| SCHEMBL9810761 | 0.80 | PYGM (0.42) | PYGM | |
| SCHEMBL9810807 | 0.80 | P2RY2 (0.49) | PYGM | |
| SCHEMBL9810803 | 0.79 | KDM4E (0.44) | PYGM | |
| SCHEMBL9810756 | 0.77 | P2RY2 (0.45) | PYGM | |
| SCHEMBL9810750 | 0.76 | PYGM (0.51) | PYGM | |
| SCHEMBL9643542 | 0.75 | PYGM (0.49) | PYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257378-B1 | PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1991-07-03 | — | — | EP | claimed |
| EP-0257378-B1 | PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1991-07-03 | — | — | EP | disclosed |