Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 2/20 | 0.45 |
| ▸ | PYGM | P11217 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810807 | 0.86 | P2RY2 (0.49) | P2RY2PYGMP2RY6 | |
| SCHEMBL9810751 | 0.85 | P2RY2 (0.43) | P2RY2PYGM | |
| SCHEMBL9780779 | 0.83 | — | — | |
| SCHEMBL9780788 | 0.83 | — | — | |
| SCHEMBL9810750 | 0.81 | PYGM (0.51) | P2RY2PYGMP2RY6 | |
| SCHEMBL9810782 | 0.81 | PYGM (0.46) | P2RY2PYGM | |
| SCHEMBL9810754 | 0.78 | PYGM (0.50) | P2RY2PYGMP2RY6 | |
| SCHEMBL9810760 | 0.78 | P2RY2 (0.44) | P2RY2PYGMP2RY6P2RY14 | |
| SCHEMBL9643485 | 0.77 | P2RY2 (0.48) | P2RY2PYGM | |
| SCHEMBL9810767 | 0.77 | PYGM (0.48) | PYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257378-B1 | PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1991-07-03 | — | — | EP | claimed |
| EP-0257378-B1 | PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1991-07-03 | — | — | EP | disclosed |