Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810765 | 1.00 | THRB (0.44) | THRBHCAR2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL3765443 | 0.91 | THRB (0.52) | THRBHCAR2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL9810757 | 0.80 | THRB (0.36) | THRBTHRACYP3A4APPTSHR | |
| SCHEMBL9601232 | 0.74 | THRB (0.58) | THRBTHRATSHRHPGDMAPT | |
| SCHEMBL27748616 | 0.73 | THRB (0.55) | THRBHCAR2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL28241610 | 0.71 | THRB (0.54) | THRBALOX5THRATSHRHPGD | |
| SCHEMBL5855841 | 0.71 | ALOX5 (0.49) | THRBHCAR2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL5855850 | 0.71 | ALOX5 (0.49) | THRBHCAR2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL148311 | 0.70 | THRB (0.55) | THRBHCAR2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL29745732 | 0.70 | THRB (0.55) | THRBHCAR2ALOX5AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171600-B1 | CARBAZOLE PHOTOINITIATORS FOR THE PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1991-06-12 | — | — | EP | disclosed |