Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 7/20 | 0.40 |
| ▸ | MAOB | P27338 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FOS | P01100 | 1/20 | 0.37 |
| ▸ | JUN | P05412 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810881 | 0.83 | NPC1 (0.41) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL28221267 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL6906151 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL29955275 | 0.81 | NPC1 (0.60) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL950478 | 0.81 | NPC1 (0.60) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL9845683 | 0.80 | MAOB (0.67) | ALDH1A1TSHRKDM4ENPC1RAB9A | |
| SCHEMBL9845680 | 0.80 | MAOB (0.67) | ALDH1A1TSHRKDM4ENPC1RAB9A | |
| SCHEMBL11176166 | 0.77 | ALDH1A1 (0.62) | ALDH1A1TSHRNPC1RAB9AMEN1 | |
| SCHEMBL9617042 | 0.77 | ALDH1A1 (0.62) | ALDH1A1TSHRNPC1RAB9AMEN1 | |
| SCHEMBL6651717 | 0.77 | KDM4E (0.74) | ALDH1A1KDM4ESMN1; SMN2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262870-B1 | MORPHOLINE, PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-06-12 | — | — | EP | disclosed |
| US-4837236-A | CONTROLLING PHYTOPATHOGENS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-06-06 | — | — | US | disclosed |
| EP-0262870-A2 | Morpholine, piperidine and tetrahydropyridine derivatives, processes for their preparation and their use as fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-04-06 | — | — | EP | disclosed |