Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.67 |
| ▸ | MAOA | P21397 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.60 |
| ▸ | CDK1 | P06493 | 1/20 | 0.60 |
| ▸ | CDK4 | P11802 | 1/20 | 0.60 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.60 |
| ▸ | CCND1 | P24385 | 1/20 | 0.60 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TLR4 | O00206 | 1/20 | 0.53 |
| ▸ | TLR2 | O60603 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845683 | 1.00 | MAOB (0.67) | MAOBMAOAALDH1A1KDM4EPKM | |
| SCHEMBL6331464 | 0.86 | MAOA (0.70) | MAOBMAOAALDH1A1KDM4EPKM | |
| SCHEMBL6331466 | 0.86 | MAOA (0.70) | MAOBMAOAALDH1A1KDM4EPKM | |
| SCHEMBL14198058 | 0.85 | MAOB (0.65) | MAOBMAOAALDH1A1KDM4EPKM | |
| SCHEMBL7006849 | 0.84 | NR1H4 (0.59) | MAOBALDH1A1KDM4ETSHRNPC1 | |
| SCHEMBL27555937 | 0.84 | NR1H4 (0.59) | MAOBALDH1A1KDM4ETSHRNPC1 | |
| SCHEMBL2496164 | 0.83 | ALDH1A1 (0.63) | MAOBMAOAALDH1A1KDM4EPKM | |
| SCHEMBL2496166 | 0.83 | ALDH1A1 (0.63) | MAOBMAOAALDH1A1KDM4EPKM | |
| SCHEMBL14045388 | 0.82 | MAOB (0.65) | MAOBMAOAALDH1A1KDM4EPKM | |
| SCHEMBL9475742 | 0.81 | KDM4E (0.60) | MAOBMAOAALDH1A1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405440-A1 | Microbicides | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | disclosed |