Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17279818 | 0.81 | MMP3 (0.54) | KMT2AMMP3BCL2L1BRD4MAPT | |
| SCHEMBL9273371 | 0.78 | BRD4 (0.46) | KMT2APCSK9BRD4MAPTKDM4E | |
| SCHEMBL23320081 | 0.75 | KMT2A (0.47) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL10940232 | 0.75 | KMT2A (0.41) | KMT2APCSK9BRD4MAPK1ALDH1A1 | |
| SCHEMBL17266867 | 0.71 | BRD4 (0.52) | KMT2APCSK9BRD4MAPTKDM4E | |
| SCHEMBL10462449 | 0.71 | HPGD (0.45) | BRD4MAPTALDH1A1HPGDCOMT | |
| SCHEMBL7359280 | 0.71 | ALDH1A1 (0.49) | KMT2AKDM4EALDH1A1CCNB2CDK1 | |
| SCHEMBL1777961 | 0.71 | ALDH1A1 (0.46) | KMT2APCSK9BRD4KDM4EMAPK1 | |
| SCHEMBL9810980 | 0.70 | BACE1 (0.51) | KMT2AMAPTKDM4EMAPK1BACE1 | |
| SCHEMBL10939190 | 0.70 | KMT2A (0.37) | KMT2APCSK9BRD4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4716236-A | Method for synthesizing esters | MILES LABORATORIES, INC. (US) | 1987-12-29 | — | — | US | claimed |
| EP-0157327-B1 | NOVEL COMPOUNDS FOR DETECTING THE PRESENCE OF HYDROLYTIC ANALYTES IN A TEST SAMPLE | MILES INC. (US) | 1991-06-12 | — | — | EP | disclosed |
| EP-0158204-B1 | COMPOSITION AND TEST DEVICE FOR DETERMINING THE PRESENCE OF LEUKOCYTES, CONTAINING A ZWITTERION COUPLING AGENT | MILES INC. (US) | 1989-11-23 | — | — | EP | disclosed |
| EP-0157326-B1 | COMPOSITION AND TEST DEVICE FOR DETERMINING THE PRESENCE OF LEUKOCYTES, ESTERASE AND PROTEASE IN A TEST SAMPLE | MILES INC. (US) | 1989-05-31 | — | — | EP | disclosed |
| US-4774340-A | AMINATION, CYCLIZATION, ESTERIFICATION | MILES INC. (US) | 1988-09-27 | — | — | US | disclosed |
| US-4716236-A | Method for synthesizing esters | MILES LABORATORIES, INC. (US) | 1987-12-29 | — | — | US | disclosed |
| US-4704460-A | LEUKOCYTES IN URINE | MILES LABORATORIES, INC. (US) | 1987-11-03 | — | — | US | disclosed |
| US-4657855-A | DIP-AND-READ, UROGENITAL DISORDERS | MILES LABORATORIES, INC. (US) | 1987-04-14 | — | — | US | disclosed |
| US-4645842-A | DETECTING LEUKOCYTES TO INDICATE KIDNEY OR UROGENITAL DISORDERS | MILES LABORATORIES, INC. (US) | 1987-02-24 | — | — | US | disclosed |
| US-4637979-A | Composition and test device for determining the presence of leukocytes containing a zwitterion coupling agent | MILES LABORATORIES, INC. (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0158226-A2 | Method of synthesizing esters | MILES INC. (US) | 1985-10-16 | — | — | EP | disclosed |
| US-4369277-A | Pyrrole-stabilized chlorine-containing thermoplastics | CIBA-GEIGY CORPORATION (US) | 1983-01-18 | — | — | US | disclosed |