Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 9/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 4/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811251 | 1.00 | CCR2 (0.37) | CCR2ALDH1A1POLBNAAACCR1 | |
| SCHEMBL9811241 | 1.00 | CCR2 (0.37) | CCR2ALDH1A1POLBNAAACCR1 | |
| SCHEMBL9811278 | 0.75 | NAAA (0.40) | CCR2ALDH1A1NAAA | |
| SCHEMBL9811270 | 0.75 | NAAA (0.40) | CCR2ALDH1A1NAAA | |
| SCHEMBL9811160 | 0.74 | ALDH1A1 (0.60) | ALDH1A1POLBNAAA | |
| SCHEMBL9811313 | 0.71 | GAA (0.57) | NAAA | |
| SCHEMBL9811238 | 0.71 | GAA (0.57) | NAAA | |
| SCHEMBL9811323 | 0.71 | GAA (0.57) | NAAA | |
| SCHEMBL20469902 | 0.66 | — | — | |
| SCHEMBL9811334 | 0.65 | NAAA (0.41) | NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202795-B1 | 4-SUBSTITUTED DIAZOLIDINONES | ELI LILLY AND COMPANY (US) | 1991-06-12 | — | — | EP | disclosed |
| US-4826993-A | Substituted diazolidinones | ELI LILLY AND COMPANY (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0202795-A1 | 4-Substituted diazolidinones | ELI LILLY AND COMPANY (US) | 1986-11-26 | — | — | EP | disclosed |