Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811375 | 0.88 | KMT2A (0.46) | KMT2ANPY5RMEN1NPY1RKDM4E | |
| SCHEMBL9620477 | 0.88 | KMT2A (0.53) | KMT2AMEN1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL9811288 | 0.88 | KMT2A (0.44) | KMT2ANPY5RMEN1NPY1RKDM4E | |
| Oxalic Acid SCHEMBL9811310 | 0.85 | KMT2A (0.43) | KMT2ANPY5RMEN1NPY1RKDM4E | |
| SCHEMBL9811463 | 0.84 | SIGMAR1 (0.40) | KMT2AMEN1KDM4ELMNAPKM | |
| SCHEMBL9620636 | 0.82 | ALDH1A1 (0.55) | KMT2AMEN1KDM4ESMN1; SMN2PKM | |
| Oxalic Acid SCHEMBL9811373 | 0.81 | KDM4E (0.40) | KMT2AMEN1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL10569654 | 0.81 | ALDH1A1 (0.46) | KMT2ANPY5RMEN1LMNACYP19A1 | |
| SCHEMBL10652015 | 0.80 | ALDH1A1 (0.47) | KMT2ANPY5RMEN1LMNAMAPT | |
| SCHEMBL9811328 | 0.79 | KMT2A (0.43) | KMT2ANPY5RMEN1NPY1RKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223124-B1 | SUBSTITUTED AMINOSULFONYL 6-NITROBENZOIC-ESTERS OR AMIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1991-06-12 | — | — | EP | claimed |
| US-4731369-A | Amides and esters of 2-(N-(hydroxypiperidinoalkyl) and (hydroxypyrrolidinoalkyl)-aminosulfonyl)-6-nitrobenzoic acids useful as adjuncts to radiation therapy | MERCK & CO. INC. (US) | 1988-03-15 | — | — | US | claimed |