Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SNRNP200 | O75643 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697049 | 0.90 | BRD4 (0.33) | BRD4BRPF1SMN1; SMN2MEN1NPC1 | |
| SCHEMBL8695583 | 0.82 | BRD4 (0.36) | BRD4BRPF1KDRSMN1; SMN2NPC1 | |
| SCHEMBL8700776 | 0.80 | BUB1 (0.33) | THRBKDRSMN1; SMN2MEN1NPC1 | |
| SCHEMBL31436154 | 0.77 | PTGER3 (0.32) | — | |
| SCHEMBL9811315 | 0.75 | BRD4 (0.32) | BRD4 | |
| SCHEMBL8697047 | 0.73 | L3MBTL1 (0.32) | SMN1; SMN2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8698470 | 0.73 | RAB9A (0.41) | KDRSMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL8695579 | 0.71 | L3MBTL1 (0.35) | SMN1; SMN2KMT2A | |
| SCHEMBL9811345 | 0.70 | ITGB1 (0.34) | THRB | |
| SCHEMBL10415296 | 0.70 | ITGB1 (0.34) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719275-A | REACTING SILYL ENOL ETHER WITH AZETIDINONE DERIVATIVE TO FORM INTERMEDIATE FOR PENICILLIN-TYPE ANTIBIOTIC | SANKYO COMPANY, LIMITED (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5681951-A | REACTING PENICILLIN DERIVATIVE HAVING SULFINYL OR SULFONYL GROUP IN 2 POSITION WITH SUBSTITUTED MERCAPTAN IN PRESENCE OF SALT OF GROUP IIA OR IIIA ELEMENT | SANKYO COMPANY, LIMITED (JP) | 1997-10-28 | — | — | US | disclosed |