Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921259 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1MAPTCYP19A1CYP1A2 | |
| SCHEMBL9233018 | 0.80 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1MAPTHTTLMNA | |
| SCHEMBL6696208 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1MAPTCYP19A1CYP1A2 | |
| SCHEMBL832001 | 0.76 | ALDH1A1 (0.71) | SMN1; SMN2ALDH1A1MAPTCYP1A2GAA | |
| SCHEMBL9659388 | 0.75 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1MAPTCYP1A2GAA | |
| SCHEMBL6694815 | 0.75 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1MAPTCYP19A1CYP1A2 | |
| SCHEMBL3712418 | 0.75 | CA2 (0.56) | ALDH1A1MAPTGAAHTTLMNA | |
| SCHEMBL9445656 | 0.75 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1CYP19A1CYP1A2GAA | |
| SCHEMBL499483 | 0.75 | GAA (0.56) | ALDH1A1MAPTGAAHTTMEN1 | |
| SCHEMBL4326710 | 0.74 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1MAPTCYP19A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0286021-B1 | REACTIVE AZO DYES | BASF Aktiengesellschaft (DE) | 1991-06-26 | — | — | EP | disclosed |
| US-4897469-A | Aniline series azo reactive dyes ortho- or para-substituted by vinyl sulfonyl reactive groups | BASF AKTIENGESELLSCHAFT (DE) | 1990-01-30 | — | — | US | disclosed |
| EP-0286021-A2 | Reactive azo dyes | BASF Aktiengesellschaft (DE) | 1988-10-12 | — | — | EP | disclosed |