SCHEMBL9811525

SCHEMBL9811525

C=CCNOC(=O)CCCCC

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
FAAH O00519 1/20 0.54
CNR2 P34972 2/20 0.53
CNR1 P21554 1/20 0.47
LMNA P02545 3/20 0.44
ALDH1A1 P00352 1/20 0.44
DGKA P23743 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.41
DNM1 Q05193 1/20 0.41
POLB P06746 1/20 0.41
POLA1 P09884 1/20 0.41
PAM P19021 2/20 0.41
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
KDM5A P29375 1/20 0.39
EPHX2 P34913 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4921535 0.87 ALDH1A1 (0.43) TSHRFAAHCNR2CNR1LMNA
SCHEMBL1133058 0.79
SCHEMBL28333098 0.79 CNR2 (0.56) TSHRFAAHCNR2CNR1LMNA
SCHEMBL3416078 0.77 CNR2 (0.63) CNR2CNR1LMNADGKAPAM
SCHEMBL22412961 0.77 CNR2 (0.63) TSHRCNR2CNR1LMNADGKA
SCHEMBL9057655 0.77 KMT2A (0.35) TSHRFAAHLMNAALDH1A1SMN1; SMN2
SCHEMBL9348111 0.77 CNR2 (0.68) TSHRCNR2CNR1LMNAALDH1A1
SCHEMBL7181018 0.76 TSHR (0.56) TSHRFAAHCNR2LMNAALDH1A1
SCHEMBL4837108 0.76 CNR2 (0.66) CNR2CNR1LMNADGKAPAM
SCHEMBL20548310 0.76 CNR2 (0.66) CNR2CNR1LMNADGKAPAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0304685-B1 PROCESS FOR THE PREPARATION OF N-ALKYLOCAPROLACTAMS BAYER AG (DE) 1991-10-16 EP claimed
US-4873326-A Process for the preparation of N-alkylated caprolactams BAYER AKTIENGESELLSCHAFT (DE) 1989-10-10 US claimed
JP-1066168-A None JP disclosed
US-4873326-A Process for the preparation of N-alkylated caprolactams BAYER AKTIENGESELLSCHAFT (DE) 1989-10-10 US disclosed