Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 17/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841930 | 0.86 | SRD5A2 (0.44) | SRD5A2CYP19A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8409403 | 0.81 | SRD5A2 (0.39) | SRD5A2CYP19A1 | |
| SCHEMBL8409113 | 0.80 | SRD5A2 (0.39) | SRD5A2CYP19A1CYP3A4 | |
| SCHEMBL6379452 | 0.80 | SRD5A2 (0.63) | SRD5A2CYP19A1 | |
| SCHEMBL15079264 | 0.80 | SRD5A2 (0.63) | SRD5A2CYP19A1 | |
| SCHEMBL17831186 | 0.80 | SRD5A2 (0.63) | SRD5A2CYP19A1 | |
| SCHEMBL17591557 | 0.80 | SRD5A2 (0.63) | SRD5A2CYP19A1 | |
| SCHEMBL9811388 | 0.77 | SRD5A2 (0.44) | SRD5A2CYP19A1CYP3A4STS | |
| SCHEMBL9811526 | 0.77 | LMNA (0.30) | CYP3A4CYP2C19 | |
| SCHEMBL8407060 | 0.76 | SRD5A2 (0.38) | SRD5A2CYP19A1CYP3A4CYP2C9STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277089-B1 | 11-BETA-ALKYNYL ESTRENES AND ESTRADIENES, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-06-12 | — | — | EP | disclosed |
| US-4870069-A | POST-COITAL FERTILITY CONTROL | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-09-26 | — | — | US | disclosed |