SCHEMBL9811549

SCHEMBL9811549

c1ccc(N(c2ccccc2)c2ccc3c(c2N(c2ccccc2)c2ccccc2)Cc2ccccc2-3)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.40
PGR P06401 1/20 0.38
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SRD5A2 P31213 1/20 0.36
HTR7 P34969 2/20 0.33
HTR2B P41595 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9811544 0.91 HSP90AA1 (0.38) PNMTPGRNPC1RAB9AALDH1A1
SCHEMBL9811589 0.88 PNMT (0.35) PNMTPGRNPC1RAB9AALDH1A1
SCHEMBL9811551 0.88 PGR (0.36) PNMTPGRNPC1RAB9AALDH1A1
SCHEMBL28435765 0.83 PNMT (0.40) PNMTPGRNPC1RAB9AALDH1A1
SCHEMBL30929930 0.83 PNMT (0.46) PNMTPGRNPC1RAB9AALDH1A1
SCHEMBL1478410 0.83 PNMT (0.46) PNMTPGRNPC1RAB9AALDH1A1
SCHEMBL8070103 0.82 PNMT (0.39) PNMTPGRNPC1RAB9AALDH1A1
SCHEMBL16577737 0.81 PNMT (0.45) PNMTPGRNPC1RAB9AALDH1A1
SCHEMBL28416939 0.81 PNMT (0.45) PNMTPGRNPC1RAB9AALDH1A1
SCHEMBL1477131 0.79 PNMT (0.46) PNMTPGRNPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5034296-A Photoconductive imaging members with fluorene polyester hole transporting layers XEROX CORPORATION (US) 1991-07-23 US claimed