Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.55 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.55 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5397033 | 0.95 | POLB (0.64) | LMNAPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL25685569 | 0.88 | POLB (0.64) | LMNAPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11212890 | 0.86 | KMT2A (0.57) | LMNAPOLBMEN1KMT2ACA12 | |
| SCHEMBL10851561 | 0.86 | RAB9A (0.57) | LMNAPOLBSMN1; SMN2CA12CA1 | |
| SCHEMBL9797681 | 0.85 | SMN1; SMN2 (0.60) | LMNAPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13634529 | 0.85 | TSHR (0.59) | LMNAPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL19555416 | 0.85 | MCL1 (0.67) | LMNAPOLBSMN1; SMN2PTPN7MCL1 | |
| SCHEMBL7489395 | 0.85 | MCL1 (0.62) | LMNAPOLBSMN1; SMN2PTPN7MCL1 | |
| SCHEMBL9274238 | 0.84 | KMT2A (0.56) | LMNAPOLBMEN1KMT2ACA12 | |
| SCHEMBL11212886 | 0.84 | CA12 (0.52) | LMNAPOLBSMN1; SMN2KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181229-B2 | Azole derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |
| EP-2687524-B1 | AZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 2015-09-30 | — | — | EP | disclosed |
| US-20140142074-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-05-22 | — | — | US | disclosed |
| US-20140142074-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-05-22 | — | — | US | disclosed |
| EP-2687524-A1 | AZOLE DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |
| US-20130345419-A1 | AZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2013-12-26 | — | — | US | disclosed |
| US-20130079313-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-03-28 | — | — | US | disclosed |
| US-20130079313-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-03-28 | — | — | US | disclosed |
| US-20100022604-A1 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR ALOPECIA | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2010-01-28 | — | — | US | disclosed |
| EP-2100588-A1 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR ALOPECIA | Taisho Pharmaceutical Co. Ltd. (JP) | 2009-09-16 | — | — | EP | disclosed |
| EP-0874805-B1 | PHENYLACETAMIDE DERIVATIVES | KOREA RES INST CHEM TECH (KR) | 2000-09-20 | — | — | EP | disclosed |
| US-5973201-A | ANALGESICS; ANTIINFLAMMATORY AGENTS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1999-10-26 | — | — | US | disclosed |
| EP-0340652-A2 | Dye sensitized photographic imaging system | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-11-08 | — | — | EP | disclosed |
| US-4859572-A | Dye sensitized photographic imaging system | EASTMAN KODAK COMPANY (US) | 1989-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022604-A1 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR ALOPECIA | PSAP, TMSB10, TSLP | LMNA 4498/4885POLB 1319/4885SMN1; SMN2 4846/4885 |
| US-20130079313-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | PDE4A, PDE4B, PDE3A | LMNA 1562/4885POLB 739/4885SMN1; SMN2 2568/4885 |
| US-20130345419-A1 | AZOLE DERIVATIVE | FKBP3, FKBP2, FKBP1A | LMNA 4761/4885POLB 4602/4885SMN1; SMN2 4859/4885 |
| US-20140142074-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | PDE4A, PDE4B, PDE3A | LMNA 1562/4885POLB 739/4885SMN1; SMN2 2568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.