Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28837409 | 0.79 | GABRP (0.47) | MAPTNPC1RAB9AHPGDCYP3A4 | |
| SCHEMBL9811801 | 0.78 | MAOB (0.50) | MAPTNPC1RAB9AHPGDCYP3A4 | |
| SCHEMBL28910311 | 0.76 | MAOB (0.48) | MAPTNPC1RAB9AHPGDCYP3A4 | |
| SCHEMBL28824618 | 0.74 | MAOA (0.49) | MAPTNPC1RAB9AHPGDCYP3A4 | |
| SCHEMBL29162696 | 0.73 | TSHR (0.46) | MAPTNPC1RAB9AHPGDCYP3A4 | |
| Hydrogen Sulfide SCHEMBL28044841 | 0.73 | MAOA (0.48) | MAPTNPC1RAB9AHPGDCYP3A4 | |
| SCHEMBL8440726 | 0.71 | MAPT (0.52) | MAPTNPC1RAB9AHPGDCYP3A4 | |
| SCHEMBL16929704 | 0.71 | MCL1 (0.50) | MAPTNPC1RAB9AHPGDCYP3A4 | |
| SCHEMBL7205104 | 0.70 | MAPT (0.56) | MAPTHPGDCYP3A4CYP1A2CYP2C19 | |
| SCHEMBL2021523 | 0.70 | MAOA (0.50) | MAPTNPC1RAB9AHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675145-B1 | Xanthene polymers and copolymers | GEN ELECTRIC (US) | 1998-11-18 | — | — | EP | disclosed |
| US-5504184-A | Xanthene polymers, and copolymers, and method for making | GENERAL ELECTRIC COMPANY (US) | 1996-04-02 | — | — | US | disclosed |
| US-5466777-A | Xanthene polymers, and copolymers, and method for making | GENERAL ELECTRIC COMPANY (US) | 1995-11-14 | — | — | US | disclosed |
| EP-0675145-A2 | Xanthene polymers and copolymers | GENERAL ELECTRIC COMPANY (US) | 1995-10-04 | — | — | EP | disclosed |