SCHEMBL9812451

SCHEMBL9812451

CCCN(CCC)CC(C)OCCN1CCCCC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 6/20 0.40
PSMB1 P20618 2/20 0.37
PSMB5 P28074 2/20 0.37
CHRNA7 P36544 1/20 0.36
ALDH1A1 P00352 1/20 0.35
LTA4H P09960 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
SLC6A4 P31645 3/20 0.34
CYP3A4 P08684 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
HIF1A Q16665 1/20 0.34
SLC22A1 O15245 1/20 0.34
CHRM2 P08172 1/20 0.34
HTR1A P08908 1/20 0.34
ADRA2A P08913 1/20 0.34
CHRM1 P11229 1/20 0.34
DRD1 P21728 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31249916 0.86 HRH3 (0.39) HRH3PSMB1PSMB5CHRNA7ALDH1A1
SCHEMBL31249944 0.84 HRH3 (0.37) HRH3PSMB1PSMB5CHRNA7ALDH1A1
SCHEMBL31249846 0.82 PSMB1 (0.41) HRH3PSMB1PSMB5CHRNA7ALDH1A1
SCHEMBL31249870 0.81 LTA4H (0.38) HRH3PSMB1PSMB5CHRNA7ALDH1A1
SCHEMBL31249889 0.80 PSMB1 (0.39) HRH3PSMB1PSMB5CHRNA7ALDH1A1
SCHEMBL31249947 0.79 PSMB1 (0.38) HRH3PSMB1PSMB5CHRNA7ALDH1A1
SCHEMBL31249946 0.79 LTA4H (0.39) HRH3PSMB1PSMB5CHRNA7ALDH1A1
SCHEMBL20326058 0.78 PSMB1 (0.41) HRH3PSMB1PSMB5CHRNA7ALDH1A1
SCHEMBL9921294 0.78 ALDH1A1 (0.45) HRH3PSMB1PSMB5CHRNA7ALDH1A1
SCHEMBL31249877 0.78 ALDH1A1 (0.37) HRH3PSMB1PSMB5CHRNA7ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5049670-A Pour point MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-09-17 US disclosed
US-4929725-A NONFLAMMABLE, HYDRAULIC FLUIDS MOORE GEORGE G I (US) 1990-05-29 US disclosed
US-4788339-A HIGH BOILING, LOW POUR POINT; HYDRAULIC FLUIDS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-11-29 US disclosed