Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.37 |
| ▸ | PRKG1 | Q13976 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9878558 | 0.87 | KDM4E (0.42) | PDE3BPDE3ALMNA | |
| SCHEMBL7272419 | 0.85 | PDE3B (0.44) | PDE3BPDE3AROCK2PRKG1LMNA | |
| SCHEMBL9543367 | 0.83 | HTT (0.46) | — | |
| SCHEMBL10665721 | 0.82 | PDE3B (0.39) | PDE3BPDE3AROCK2PRKG1LMNA | |
| SCHEMBL10666182 | 0.81 | PDE3B (0.38) | PDE3BPDE3AROCK2PRKG1LMNA | |
| SCHEMBL14449885 | 0.79 | SLC6A3 (0.36) | — | |
| SCHEMBL13920733 | 0.79 | SLC6A3 (0.36) | — | |
| SCHEMBL13920693 | 0.79 | KDM4E (0.43) | LMNADDB1CRBN | |
| SCHEMBL13920699 | 0.79 | HCAR2 (0.39) | LMNA | |
| SCHEMBL791422 | 0.78 | MAPK1 (0.41) | MMP2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047545-A | 2-alkoxycarbonyl-4-(4-pyridyl)cyclohexanones and process for preparing them | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-09-10 | — | — | US | claimed |
| EP-0281661-B1 | 2-ALKOXYCARBONYL-4-(4-PYRIDYL)CYCLOHEXANONES AND PROCESS FOR PREPARING THEM | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-07-17 | — | — | EP | claimed |
| CN-87101872-A | 2-carbalkoxy-4-(4-pyridyl) pimelinketone and preparation method thereof | — | 1988-09-21 | — | — | CN | claimed |
| EP-0281661-A1 | 2-Alkoxycarbonyl-4-(4-pyridyl)cyclohexanones and process for preparing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-09-14 | — | — | EP | claimed |
| US-5047545-A | 2-alkoxycarbonyl-4-(4-pyridyl)cyclohexanones and process for preparing them | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-09-10 | — | — | US | disclosed |
| US-5047545-A | 2-alkoxycarbonyl-4-(4-pyridyl)cyclohexanones and process for preparing them | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0281661-B1 | 2-ALKOXYCARBONYL-4-(4-PYRIDYL)CYCLOHEXANONES AND PROCESS FOR PREPARING THEM | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-07-17 | — | — | EP | disclosed |
| EP-0281661-A1 | 2-Alkoxycarbonyl-4-(4-pyridyl)cyclohexanones and process for preparing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-09-14 | — | — | EP | disclosed |
| EP-0281661-A1 | 2-Alkoxycarbonyl-4-(4-pyridyl)cyclohexanones and process for preparing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-09-14 | — | — | EP | disclosed |