Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6229686 | 0.87 | TSHR (0.50) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL9813079 | 0.87 | PDE3B (0.40) | PDE3BPDE3ALMNA | |
| SCHEMBL31067212 | 0.85 | LMNA (0.42) | KDM4EALDH1A1MAPTGAAESR2 | |
| SCHEMBL10665721 | 0.83 | PDE3B (0.39) | KDM4EMAPTPDE3BPDE3ATLR4 | |
| SCHEMBL7272419 | 0.81 | PDE3B (0.44) | ALDH1A1MAPTPDE3BPDE3AESR2 | |
| SCHEMBL31067236 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TSHRACHELMNA | |
| SCHEMBL10666182 | 0.77 | PDE3B (0.38) | ALDH1A1MAPTPDE3BPDE3AESR2 | |
| SCHEMBL31067210 | 0.75 | BRD4 (0.43) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL18366148 | 0.74 | TP53 (0.41) | KDM4EALDH1A1MAPTESR2MEN1 | |
| SCHEMBL10356214 | 0.74 | SMN1; SMN2 (0.42) | PDE3BPDE3AMEN1KMT2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047545-A | 2-alkoxycarbonyl-4-(4-pyridyl)cyclohexanones and process for preparing them | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-09-10 | — | — | US | claimed |