Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813093 | 0.90 | ALDH1A1 (0.36) | MEN1KMT2AESR1ESR2ATM | |
| SCHEMBL11334473 | 0.74 | ESR2 (0.45) | MEN1KMT2AESR1ESR2ALDH1A1 | |
| SCHEMBL11385199 | 0.73 | ALDH1A1 (0.43) | MEN1KMT2AESR1ESR2ATM | |
| SCHEMBL2347168 | 0.73 | ALDH1A1 (0.43) | MEN1KMT2AESR1ESR2ATM | |
| SCHEMBL8795201 | 0.73 | GAA (0.45) | MEN1KMT2AESR1ESR2ATM | |
| SCHEMBL9592812 | 0.73 | CNR2 (0.43) | MEN1KMT2AALDH1A1HTTPOLB | |
| SCHEMBL3907809 | 0.72 | ALDH1A1 (0.45) | MEN1KMT2AESR1ESR2ALDH1A1 | |
| SCHEMBL6062172 | 0.71 | TSHR (0.49) | MEN1KMT2AESR1ESR2ALDH1A1 | |
| SCHEMBL8459792 | 0.70 | ALDH1A1 (0.44) | MEN1KMT2AESR1ESR2ATM | |
| SCHEMBL9511076 | 0.70 | SMN1; SMN2 (0.42) | MEN1KMT2AESR1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304780-B1 | PROCESS FOR LABELLING SUBSTANCES WITH TECHNETIUM OR RHENIUM | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-07 | — | — | EP | disclosed |