Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9174275 | 0.86 | ALDH1A1 (0.55) | ALDH1A1HPGDMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9811205 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL9811018 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HPGDMAPTSMN1; SMN2ALOX5 | |
| SCHEMBL10597158 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9811102 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTSMN1; SMN2KDM4E | |
| SCHEMBL11111617 | 0.75 | ALDH1A1 (0.64) | ALDH1A1HPGDMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9175427 | 0.74 | SMN1; SMN2 (0.56) | ALDH1A1HPGDMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9811218 | 0.74 | ALDH1A1 (0.59) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL10358654 | 0.73 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL10763608 | 0.72 | ALDH1A1 (0.54) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161220-B1 | PROCESS FOR THE PREPARATION OF BETA-(BENZOTHIAZOLYLTHIO) AND BETA (BENZIMIDAZOLYLTHIO)CARBOXYLIC-ACID DERIVATIVES | CIBA-GEIGY AG (CH) | 1991-08-14 | — | — | EP | disclosed |
| EP-0161220-A2 | Process for the preparation of beta-(benzothiazolylthio) and beta (benzimidazolylthio)carboxylic-acid derivatives | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |