Hydrochloric Acid

Hydrochloric Acid

SCHEMBL9813245

CCCCCCCCCCCCCCC(O)C[N+](C)(C)CCO.CCCCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCCCC.[Cl-].[Cl-]

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PLA2G1B P04054 3/20 0.84
ATG4B Q9Y4P1 3/20 0.84
PSMD14 O00487 2/20 0.84
MMP2 P08253 2/20 0.84
HSP90AA1 P07900 2/20 0.84
RAD52 P43351 2/20 0.69
DNM1 Q05193 7/20 0.65
HTT P42858 2/20 0.48
GPR84 Q9NQS5 4/20 0.42
KMT2A Q03164 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8362466 0.95 PSMD14 (0.93) PLA2G1BATG4BPSMD14MMP2HSP90AA1
Hydrochloric Acid SCHEMBL2185310 0.95 PSMD14 (0.93) PLA2G1BATG4BPSMD14MMP2HSP90AA1
Hydrochloric Acid SCHEMBL10482719 0.95 PSMD14 (0.93) PLA2G1BATG4BPSMD14MMP2HSP90AA1
Hydrochloric Acid SCHEMBL178234 0.95 PSMD14 (0.93) PLA2G1BATG4BPSMD14MMP2HSP90AA1
SCHEMBL10580148 0.93 PSMD14 (0.96) PLA2G1BATG4BPSMD14MMP2HSP90AA1
SCHEMBL1054173 0.93 PSMD14 (0.96) PLA2G1BATG4BPSMD14MMP2HSP90AA1
Fluoride Ion SCHEMBL9805580 0.92 PSMD14 (0.93) PLA2G1BATG4BPSMD14MMP2HSP90AA1
Hydrochloric Acid SCHEMBL11527519 0.92 PLA2G1B (0.74) PLA2G1BATG4BPSMD14MMP2HSP90AA1
Hydrochloric Acid SCHEMBL11595988 0.92 PLA2G1B (0.74) PLA2G1BATG4BPSMD14MMP2HSP90AA1
Hydrochloric Acid SCHEMBL28668483 0.92 PLA2G1B (0.74) PLA2G1BATG4BPSMD14MMP2HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0437462-A1 USE OF AMPHOTERIC AND ZWITTERIONIC CELLULOSE ETHERS IN HAIR CARE PRODUCTS Henkel Kommanditgesellschaft auf Aktien (DE) 1991-07-24 EP disclosed
WO-1990003779-A1 USE OF AMPHOTERIC AND ZWITTERIONIC CELLULOSE ETHERS IN HAIR CARE PRODUCTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1990-04-19 WO disclosed