Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813248 | 0.73 | MEN1 (0.44) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9813319 | 0.72 | NPC1 (0.41) | ALDH1A1KDM4EMAPK1NPC1RAB9A | |
| SCHEMBL9813250 | 0.71 | MAPT (0.39) | ALDH1A1KDM4EMAPK1NPC1RAB9A | |
| SCHEMBL8599835 | 0.70 | MAOA (0.54) | ALDH1A1KDM4EMAPK1HTTMEN1 | |
| SCHEMBL8530083 | 0.69 | CYSLTR1 (0.49) | — | |
| SCHEMBL27815401 | 0.69 | NPC1 (0.51) | ALDH1A1KDM4EMAPK1NPC1RAB9A | |
| SCHEMBL2786872 | 0.68 | GAA (0.53) | ALDH1A1KDM4ENPC1RAB9APDE5A | |
| SCHEMBL10464685 | 0.68 | PDE5A (0.41) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6584892 | 0.68 | SMN1; SMN2 (0.45) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22930413 | 0.67 | KDM4E (0.34) | ALDH1A1KDM4EKCNA5GAACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153709-B1 | NOVEL CEPHALOSPORIN DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4785090-A | ANTIBIOTICS, BACTERICIDES | MEIJI SEIKA KAISHA, LTD. (JP) | 1988-11-15 | — | — | US | disclosed |
| US-4608373-A | BACTERICIDES, ANTIBIOTICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-08-26 | — | — | US | disclosed |
| EP-0153709-A2 | Novel cephalosporin derivatives | MEIJI SEIKA KAISHA LTD. (JP) | 1985-09-04 | — | — | EP | disclosed |
| EP-0112164-A2 | Cephem compounds, and their production, and medicaments containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1984-06-27 | — | — | EP | disclosed |