Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20987960 | 0.82 | ALDH1A1 (0.63) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL13140638 | 0.78 | NPC1 (0.61) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL9813319 | 0.77 | NPC1 (0.41) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL2481128 | 0.76 | MEN1 (0.47) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL1556923 | 0.75 | MAPT (0.52) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL27815401 | 0.75 | NPC1 (0.51) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL9813253 | 0.73 | ALDH1A1 (0.40) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL2786872 | 0.73 | GAA (0.53) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL10464685 | 0.73 | PDE5A (0.41) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL6584892 | 0.73 | SMN1; SMN2 (0.45) | MEN1KMT2APOLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153709-B1 | NOVEL CEPHALOSPORIN DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4785090-A | ANTIBIOTICS, BACTERICIDES | MEIJI SEIKA KAISHA, LTD. (JP) | 1988-11-15 | — | — | US | disclosed |
| US-4608373-A | BACTERICIDES, ANTIBIOTICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-08-26 | — | — | US | disclosed |
| EP-0153709-A2 | Novel cephalosporin derivatives | MEIJI SEIKA KAISHA LTD. (JP) | 1985-09-04 | — | — | EP | disclosed |
| EP-0112164-A2 | Cephem compounds, and their production, and medicaments containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1984-06-27 | — | — | EP | disclosed |