Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GRK2 | P25098 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768512 | 0.87 | MGLL (0.50) | CA2KMT2APOLBGRK2ALDH1A1 | |
| SCHEMBL10584133 | 0.83 | KMT2A (0.58) | CA2KMT2APOLBGRK2ALDH1A1 | |
| SCHEMBL9320853 | 0.83 | GAA (0.62) | CA2KMT2AALDH1A1HDAC1HDAC8 | |
| SCHEMBL10580731 | 0.83 | HDAC1 (0.56) | KMT2APOLBGRK2ALDH1A1HDAC1 | |
| SCHEMBL3250400 | 0.83 | TBXA2R (0.62) | CA2CA12CA1CA9KMT2A | |
| SCHEMBL9813778 | 0.81 | ALDH1A1 (0.45) | KMT2APOLBGRK2ALDH1A1HDAC1 | |
| SCHEMBL10582606 | 0.81 | ALDH1A1 (0.39) | CA2CA12CA1CA4CA6 | |
| SCHEMBL9813459 | 0.81 | ALDH1A1 (0.39) | CA2CA12CA1CA4CA6 | |
| SCHEMBL9813846 | 0.80 | LTB4R (0.55) | KMT2APOLBGRK2ALDH1A1HDAC1 | |
| SCHEMBL9813760 | 0.80 | KMT2A (0.47) | KMT2APOLBGRK2ALDH1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301421-B1 | SULFUR COMPOUNDS, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |
| EP-0297768-B1 | ARYLTHIOALKYLPHENYL CARBOXYLIC ACIDS, COMPOSITIONS CONTAINING SAME AND METHOD OF USE | E.R. Squibb & Sons, Inc. (US) | 1991-07-24 | — | — | EP | disclosed |
| EP-0301421-A2 | Sulfur compounds, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1989-02-01 | — | — | EP | disclosed |
| EP-0297768-A1 | Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use | E.R. Squibb & Sons, Inc. (US) | 1989-01-04 | — | — | EP | disclosed |
| US-4752616-A | Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use | E. R. SQUIBB & SONS, INC. (US) | 1988-06-21 | — | — | US | disclosed |